Laboratory Manager, Endodermal Organoid Laboratory

Location: Basel, Basel-city, Switzerland

Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.

The Position

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

You will join Roche’s Institute of Human Biology, an organization within pRED whose goal is to harness and advance the use of human model systems in drug discovery and development, as well as personalized medicine. Our interdisciplinary research bridges academic and pharmaceutical research, connecting biologists, engineers, and data scientists.

With the continued expansion of the IHB and the upcoming move to a new building, we are seeking a new Lab Manager for organizational and lab support. In this role, you will be responsible for maintaining lab spaces across the IHB, as well as directly contributing to ongoing research projects.

Role mission

As the Lab manager for the IHB, you will support the establishment of a newly formed IHB, whose goal is to disrupt the traditional drug discovery process through innovative and bold ideas focused on advancing more predictive human model systems. You will help establish and lab spaces focused on human in-vitro systems, working in the newly formed Endodermal Organoid Group. Furthermore, you will work closely with the Lead Scientists of every lab to ensure the proper and compliant use of lab workspaces for the members of the teams. In addition, you will aid and/or coordinate inter- and intra- Institute lab spaces and equipment. Moreover, you will work in close collaboration with other scientists to provide access to standard operating procedures (SOP). This is a rare opportunity to be involved in supporting the creation and growth of a new and exciting environment that brings together scientists and engineers from around the world.

Your Impact

• Manage tissue processing lab & primary cell culture, including relevant equipment maintenance, reagent ordering and ensuring smooth and efficient general lab operations.
• Support day to day activities in the lab and assist with training young scientists, maintaining order in the lab, coordinating lab cleaning, etc.
• Train and assist IHB colleagues with tissue processing, organoid derivation and organoid culture techniques, including onboarding new team members
• Perform mycoplasma tests on organoids and cell lines.
• Ensure SHE compliance and good working practices within tissue processing & primary cell culture labs

Your Profile

You are someone who wants to influence your development. You are looking for a company where you can pursue your interests across functions and geographies. Where a job title is not considered the final definition of who you are, but the starting point. The ideal candidate for our dynamic, international team will have the following skills and experience:

• Bachelor or Master degree in biology, bioengineering or related field with a minimum of 3 years of experience.
• Handling and processing of primary tissue samples (tumor and healthy tissues) to derive and expand organoids, immune and stromal cells.
• Hands-on experience in
  • Organoid culture and Primary cell culture
  • Molecular technologies, including transfections, use of CRISPR tools, immunohistochemistry
  • Flow cytometry
• Exceptional organizational, interpersonal and communication skills.
• Experience with iPSC, tissue-derived organoid models and Histo-Pathology would be considered an asset.

Please include a cover letter, a CV, and the names of three references.

The position is temporary for 2 years.

Our commitment

Roche commits to recognizing talent and aptitude. We prioritize encouraging and supporting our employees on their personal journeys by providing a safe, creative space to help them reflect, make decisions and grow in their career.

We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo. Roche embraces diversity and equal opportunity in a serious yet enthusiastic way; we are devoted to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.  

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.

Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.

We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.

Roche is an Equal Opportunity Employer.