Nikolche Gjorevski leads the Organoid Engineering group at IHB.
His research focuses on using bioengineering approaches to understand the multicellular interactions that drive tissue development and disease. By reconstituting these fundamental processes, his group aims to engineer better preclinical models for drug development. This work is critical for improving our ability to predict human responses to novel therapeutics and for gaining deeper insights into human biology.
Nikolche joined IHB in 2021. Before this, he was a Senior Scientist and Lab Head in Pharmaceutical Sciences at Roche’s R&D unit, Pharma Research and Early Development (pRED), in Switzerland. His scientific contributions include developing alternatives to animal-derived matrices for organoid culture, and pioneering approaches to control the shape of organoids as a means to enhance their reproducibility, architectural fidelity and function. More recently, his work has focused on engineering physiological and pathological immune responses within organoids. He conducted his postdoctoral fellowship at EPFL in Lausanne, Switzerland, and received his PhD in chemical and biological engineering from Princeton University, USA.
Nikolche’s work has been recognized with numerous honors, including the prestigious EMBO Long-Term Postdoctoral Fellowship, the Wallace Memorial Fellowship from Princeton University, and multiple Roche 3Rs Awards for his contributions to developing alternative preclinical models. He is also a member of the Phi Beta Kappa and Tau Beta Pi honor societies.
