Our Exploratory Research core includes academic-style basic science projects addressing open questions, and hypothesis- or discovery-driven. Expected outcomes are new biological insights (e.g., pathway, target, mechanism, etc.) or ground-breaking new tools or engineering concepts. The Exploratory Research core will be expanding over the next months.
We use single-cell genomic, imaging, and stem cell bioengineering technologies to explore human development and disease. Broadly, we like to think about how cell fates and states are established during organ formation, how diverse cells organise themselves in complex microenvironments, and how disrupted cell ecosystems lead to disease. We use and develop high-information content measurements and computational methods to explore these topics. Currently we work primarily on development and disorders of the central nervous system and gastrointestinal tract. We are also interested in how human organs are different from other species, and how human evolution has led to disease susceptibilities.
We are always looking for talented individuals.
